Strategies for drug target identification in Mycobacterium leprae
نویسندگان
چکیده
منابع مشابه
Computational genome analyses of metabolic enzymes in Mycobacterium leprae for drug target identification
Leprosy is an infectious disease caused by Mycobacterium leprae. M. leprae has undergone a major reductive evolution leaving a minimal set of functional genes for survival. It remains non-cultivable. As M. leprae develops resistance against most of the drugs, novel drug targets are required in order to design new drugs. As most of the essential genes mediate several biosynthetic and metabolic p...
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ژورنال
عنوان ژورنال: Drug Discovery Today
سال: 2021
ISSN: 1359-6446
DOI: 10.1016/j.drudis.2021.03.026